Stocks that moved substantially or traded heavily Wednesday on the New York Stock Exchange and the Nasdaq stock market:
NYSE
Chipotle Mexican Grill Inc., down $22.36 to $426.67
The fast-food chain received a federal grand jury subpoena as the government looks into a norovirus outbreak at a California restaurant.
TherapeuticsMD Inc., down 93 cents to $8.38
The women's health products company is publicly offering $125 million in stock and will used proceeds for sales and development.
Valeant Pharmaceuticals International Inc., up $1.54 to $102.40
The drug developer named Howard Schiller as interim CEO to replace Michael Pearson, who remains hospitalized from pneumonia.
AutoNation Inc., down $5.98 to $50.76
The auto retailer had to offer large discounts in December and will report smaller profits per vehicle in the fourth quarter.
Nasdaq
Netflix Inc., up $10.02 to $117.68
The video streaming company said it was launching its service globally and added service in several new languages including Arabic and Korean.
Conatus Pharmaceuticals Inc., up 1 cent to $2.88
The biotechnology company reported positive results from a mid-stage study on a potential treatment for liver diseases.
Epizyme Inc., down $3.58 to $11.54
The biotechnology company plans to publicly offer $120 million in stock, mainly to fund development of cancer treatments.
Cempra Inc., down $3.99 to $24.74
The drug developer plans to offer $175 million in stock to fund development of antibiotics for bacterial infectious diseases.
This content appears as provided to The Globe by the originating wire service. It has not been edited by Globe staff.