Second-seeded Simona Halep and Venus Williams both lost in the opening round of the Madrid Open on Sunday, while top-seeded Serena Williams had a trouble-free debut.
Defending champion Maria Sharapova also advanced after beating Timea Bacsinszky 6-2, 6-3.
Halep, the 2014 French Open finalist, failed to convert two set points in the first set before losing 7-6 (6), 6-3 to Alize Cornet of France.
Serena Williams defeated American Madison Brengle 6-0, 6-1 after breaking her six times to win in less than an hour.
Venus Williams, however, lost to fellow former No. 1 Victoria Azarenka 6-3, 7-5.
Venus, seeded 16th, went up a break at 4-3 in the second set, only for Azarenka to win four of the next five games.
This content appears as provided to The Globe by the originating wire service. It has not been edited by Globe staff.