Metabolon's Metabolomics Platform Enables Largest Metabolomic Analysis to Date in CAR T-Cell Therapy, Revealing New Insights into Severe Neurotoxicity

Metabolomics-Derived Pathway Scores Outperform Inflammatory Protein Markers--Delivering Risk Prediction Where Proteomics Falls Short

MORRISVILLE, N.C., Feb. 17, 2026 /CNW/ -- Metabolon, Inc., the global leader in providing metabolomics solutions advancing a wide variety of life science research, diagnostic, therapeutic development, and precision medicine applications, today announced its industry-leading global metabolomics platform was used by researchers from Kite, a Gilead company, for the most extensive metabolomic study ever conducted in the context of CAR T-cell therapy. Leveraging Metabolon's untargeted Global Discovery Panel, Kite researchers analyzed more than 3,800 longitudinal serum and plasma samples--and a rare set of cerebrospinal fluid (CSF) samples--from patients treated with the FDA-approved anti-CD19 CAR T-cell therapies axicabtagene ciloleucel (axi-cel) and brexucabtagene autoleucel (brexu-cel).