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Tiziana Life Sciences Completes Enrollment in Phase 2 Intranasal Foralumab MS Trial

Tipranks - Fri May 22, 11:08AM CDT

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The latest announcement is out from Tiziana Life Sciences ( (TLSA) ).

On May 21, 2026, Tiziana Life Sciences reported completion of patient enrollment in its INFORM-MS study, a randomized, double-blind, placebo-controlled Phase 2a trial of intranasal foralumab in non-active secondary progressive multiple sclerosis. The multicenter U.S. trial has enrolled 48 patients who will receive two dose levels or placebo over 12 weeks, followed by a six-month open-label extension to assess long-term safety and sustained benefit.

The INFORM-MS trial is described as the first placebo-controlled Phase 2 study of intranasal foralumab, and includes PET imaging for microglial activation, MRI and biomarker assessments to probe its immune-modulating effects. Topline data are expected in late third quarter 2026 and are slated to be presented at the ACTRIMS-ECTRIMS joint meeting in Toronto in October, a timeline that could influence Tiziana’s positioning in the multiple sclerosis space if results support a new, non-invasive treatment approach for na-SPMS.

The most recent analyst rating on (TLSA) stock is a Buy with a $8.00 price target. To see the full list of analyst forecasts on Tiziana Life Sciences stock, see the TLSA Stock Forecast page.

More about Tiziana Life Sciences

Tiziana Life Sciences is a clinical-stage biopharmaceutical company focused on developing immunotherapy-based treatments using alternative drug delivery technologies, particularly intranasal administration. Its lead asset is intranasal foralumab, a fully human anti-CD3 monoclonal antibody positioned for neuroinflammatory and neurodegenerative diseases, with a pipeline supported by patented delivery platforms.

Average Trading Volume: 155,253

Technical Sentiment Signal: Strong Buy

Current Market Cap: $191.4M

For detailed information about TLSA stock, go to TipRanks’ Stock Analysis page.

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