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Carolina Panthers' Graham Gano celebrates with Michael Palardy after kicking a 48-yard field goal during the fourth quarter to defeat the New England Patriots 33-30 at Gillette Stadium in Foxboro, Massachusetts, on Oct. 1, 2017.Jim Rogash/Getty Images

Graham Gano hit a 48-yard field goal as time expired, and the Carolina Panthers stunned the New England Patriots 33-30 on Sunday.

The winner served as redemption for Gano, who missed an extra point in the third quarter.

It was the second home loss this season for the usually unbeatable Patriots at Gillette Stadium. The defeat marked just the second time since 2012 that Tom Brady has lost two home starts within a season.

Cam Newton threw for three touchdowns and ran for another. Jonathan Stewart rushed 14 times for 68 yards to pass DeAngelo Williams and become the franchise's all-time leading rusher.

Newton finished 22 of 29 for 316 yards and an interception, picking apart a New England defence that was giving up an NFL-worst 461 yards and 31.7 points per game. The Patriots (2-2) forced a pair of turnovers, but had trouble containing Newton's stable of targets.

Carolina (3-1) finished with 444 total yards, marking the fourth straight game the Patriots have given up at least 300 yards.

Brady finished 32 of 45 for 307 yards and two scores.

RAMS 35, COWBOYS 30

Todd Gurley scored the go-ahead touchdown on a 53-yard catch-and-run, and Greg Zuerlein kicked a career-high seven field goals.

Gurley finished with 215 total yards – 121 rushing and 94 receiving – as the Rams overcame two first-half touchdowns from Ezekiel Elliott the day before a federal appeals court hearing related to the star Dallas running back's blocked six-game suspension over a domestic incident in Ohio.

The Rams (3-1) rallied from 11 points down late in the first half and matched their start from a year ago, when they went 1-11 the rest of the way as No. 1 overall pick Jared Goff was sitting and later lost the first seven starts of his career.

Goff showed more poise in first-year coach Sean McVay's offence, throwing for 255 yards and two touchdowns without an interception. He has seven TD passes and one interception this season.

The Cowboys (2-2) are already a loss shy of their total from last season when Dak Prescott was the NFL Offensive Rookie of the Year and Elliott led the league in rushing, also as a rookie.

BILLS 23, FALCONS 17

Stephen Hauschka kicked a tiebreaking, 56-yard field goal with less than five minutes remaining and the Buffalo Bills made a last-minute defensive stand.

The Falcons lost star wide receiver Julio Jones to a hip injury and also saw fellow WR Mohamed Sanu (hamstring) leave the game.

Hauschka padded the lead with a 55-yarder with about three minutes remaining.

Buffalo's defence stopped the Falcons at the Bills 10 with less than a minute remaining when Matt Ryan couldn't complete a fourth-down pass to Taylor Gabriel, and Atlanta became the last NFC team to lose this season.

Tre'Davious White returned a fumble recovery 52 yards for a third-quarter touchdown as the tough Buffalo defence delivered again even when it yielded its first passing touchdown of the season. Bills defensive end Jerry Hughes hit Ryan's arm as Ryan was trying to pass, forcing the fumble.

It was one of three turnovers by Atlanta (3-1) on a day the Bills (3-1) set a team record for consecutive quarters without a turnover. Ryan threw two interceptions, giving him five in his last two games.

STEELERS 26, RAVENS 9

Le'Veon Bell rushed for 144 yards and two touchdowns to seize first place in the AFC North.

Though held to a touchdown over the final 30 minutes, Pittsburgh (3-1) mounted enough of an attack before halftime to earn its first win in Baltimore since 2012. Ben Roethlisberger went 18 for 30 for 216 yards and a touchdown. Bell did more than his share, carrying the ball 35 times to help the Steelers amass 381 yards on offence.

The Ravens (2-2), meanwhile, looked every bit like the 32nd-ranked offence in the NFL. Baltimore trailed 19-0 at halftime, generated only 154 yards through three quarters and stumbled through a second straight game with only one touchdown.

Joe Flacco completed 31 of 49 passes for 235 yards, was sacked four times and intercepted twice.

TEXANS 57, TITANS 14

Rookie Deshaun Watson threw for four touchdowns and ran for another as the Texans scored the most points in franchise history.

Watson, the 12th pick in this year's draft, became the first rookie to throw four touchdowns and run for another one since Fran Tarkenton in 1961, and tied an NFL record for most TDs by a rookie quarterback.

The Texans (2-2) outdid their previous highest point total of 45 set in a victory over the Titans in 2014 and are the first NFL team to score 50 points since the Jaguars scored 51 in December 2015.

Houston's defence got things going when Andre Hal intercepted Marcus Mariota on the game's third play. It was the first of four interceptions for Houston's defence. Mariota, who became the first Titans quarterback with two rushing touchdowns in a game since Steve McNair in 2003, injured his hamstring and didn't play after halftime. Matt Cassel took over for the Titans (2-2) and threw for 21 yards with two interceptions.

Watson then led Houston's offence to touchdowns on three straight possessions for a 21-0 lead early in the second quarter. It was the first time since Oct. 19, 2008 that Houston scored a touchdown on each of its first three possessions.

LIONS 14, VIKINGS 7

Anthony Zettel led a ferocious performance by Detroit's defence with two sacks, four hurries and a fumble recovery, as the Lions forced three turnovers while holding Minnesota scoreless in the second half.

The Lions turned two fumbles lost by the Vikings in the third quarter into 11 points, taking the lead on Ameer Abdullah's 1-yard touchdown run five plays after rookie Dalvin Cook fumbled at the Minnesota 29.

The Vikings (2-2) lost more than just possession when Cook limped off with an injury to his left knee and did not return.

Tahir Whitehead recovered that fumble for the Lions, plus one by Adam Thielen with 1:43 left at the Detroit 45 that ended the last-chance drive for the Vikings.

Detroit (3-1) leads the NFL in turnover margin at plus-9.

Abdullah came close to ending a four-year stretch by the Lions without a 100-yard rusher, finishing with 94 yards on 20 carries before leaving with an undisclosed injury.

Matthew Stafford was sacked six times for 55 yards, but he hung on to the ball each time and completed 19 of 31 passes for 209 yards, plus the key 2-point conversion to T.J. Jones to give the Lions a seven-point lead.

Case Keenum started in place of Sam Bradford at quarterback for the Vikings for the third straight game, going 16 for 30 for 219 yards. He was sacked by Zettel for an 11-yard loss on third-and-goal from the 3 right before the two-minute warning, and his fourth down heave into the end zone sailed over Thielen's head.

SAINTS 20, DOLPHINS 0

Drew Brees threw for 268 yards and two touchdowns and the Saints scored all but three of their points in the second half.

Michael Thomas had a touchdown reception in the third quarter, Alvin Kamara added one in the fourth and Will Lutz made two of his three field-goal attempts for New Orleans (2-2), which arrived for the game on Monday and won the lowest-scoring game ever held in London.

It was expected to be a big homecoming for the Dolphins' Jay Ajayi, who was born in the city, but the running back finished with 46 yards on 12 carries.

Lutz missed his first try, a 41-yarder, wide right on the second play of the second quarter, and the teams threatened to have the first scoreless opening half since Week 14 of the 2011 season until Lutz connected from 43 yards with no time remaining.

Brees found Thomas, who had eight catches for 89 yards, on a 4-yarder to push the score to 10-0 in the third quarter, and Kamara took a shovel pass from Brees 12 yards into the end zone with 3:57 remaining to wrap up the victory.

JETS 23, JAGUARS 20, OT

Chandler Catanzaro kicked a 41-yard field goal with 28 seconds left in overtime, lifting the Jets to a wacky win.

After Catanzaro split the uprights, he and his teammates celebrated wildly in the middle of the field – but then had to wait because there was a penalty flag on the field. The officials ruled there actually was no penalty on the play, giving the Jets the victory.

Bilal Powell rushed for a career-high 163 yards, including a 75-yard touchdown, and rookie Elijah McGuire had a 69-yard score and finished with 93 yards rushing as the Jets (2-2) ran all over the Jaguars (2-2).

But New York blew a 10-point, fourth-quarter lead because of some big mistakes, then had to hold on in the extra period.

After Jacksonville went three-and-out, on the punt Paul Posluszny was called for unsportsmanlike conduct for taunting as the Jets' Dylan Donahue went down on the Jaguars sideline with an elbow injury. It put the ball on the Jacksonville 25, and after two 1-yard runs, Josh McCown spiked the ball to set up Catanzaro's field goal.

McCown finished 22 of 31 for 224 yards with an interception and the Jets outgained the Jaguars 471-311 in total yards, including 256-175 on the ground.

BENGALS 31, BROWNS 7

Andy Dalton threw three of his four touchdown passes in the first half and Cincinnati's offence found the perfect opponent to work out some early season struggles.

Dalton only missed on one of 18 throws in the first half as the Bengals (1-3) built a 21-0 lead.

He connected with A.J. Green, Tyler Croft and Giovani Bernard while dissecting the young Browns (0-4), who were again plagued by mistakes and were down three defensive starters.

Dalton, the NFL's 30th-ranked QB, finished 25 of 30 for 286 yards. His second TD to Croft in the third quarter made it 31-0, and sent even some of the most die-hard Browns fans toward the FirstEnergy Stadium exits.

The Browns avoided a shutout with 1:54 left.

NBA Commissioner Adam Silver says the National Anthem is a 'moment of reflection' before games in which all players are required to participate.

The Associated Press

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