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Israeli security forces examine a fragment of an intercepted Iranian missile in northern Israel.Rami Shlush/The Associated Press

Israel launched airstrikes early Monday targeting central and western Iran in response to missile fire from Tehran, attacks that threatened to drag the wider Middle East back into a regional war.

Iranian state television reported the sound of explosions being heard in Isfahan, Karaj, Tabriz and Tehran, without immediately elaborating. A witness in Tehran described hearing at least one large blast somewhere to the west of the country’s capital city. Iran closed the airspace around Tehran’s Imam Khomeini International Airport, the country’s main airfield, after the Israeli attack.

Iranian officials offered no details on what had been struck, nor any damage information. Iran’s paramilitary Revolutionary Guard said that Israel used air-launched ballistic missiles in its attack Monday morning, without elaborating.

The Israeli military at dawn in Iran issued a short statement as the strikes started: “A short while ago, the Israeli Air Force struck military targets belonging to the Iranian terror regime in western and central Iran.” It did not elaborate.

The White House did not respond to messages about the strikes and whether they were done in coordination with the U.S.

For days, negotiations between Iran and the United States over the fragile ceasefire in the war had been stalled by the fighting between Israel and the Lebanese Shiite militia Hezbollah. Israel now occupies southern Lebanon and had moved into areas of the country it hadn’t held in a quarter century — leading to fears about them further widening their campaign.

On Sunday, Israel launched airstrikes in Beirut’s southern suburbs. Iran retaliated with its own strike on Israel, which led to Monday morning’s attack by Israel on Iran.

U.S. President Donald Trump earlier told a Fox News Channel reporter that he wanted the Iranians to stop firing missiles and return to the negotiating table. He also said that Israel’s strikes in Lebanon earlier Sunday were not coordinated with the U.S. and “I’m not happy about it.”

A senior U.S. official said Trump had called Netanyahu to urge him not to retaliate immediately for the Iranian missile attack. The official, who spoke on condition of anonymity to describe a private phone call, said that Trump believed he had convinced Netanyahu to wait.

Trump “got Bibi to hold off for the time being,” the official said. The official would not offer any other details of the call, and there was no immediate comment from Netanyahu’s office.

Iran launches missile attacks on Gulf neighbours in ‘serious escalation’

Earlier, Iran launched missiles at Israel in the first such bombardment since a fragile ceasefire took effect in early April. The exchange raised the possibility of a return to heavy fighting and complicating mediation efforts to end the war.

Iran’s state broadcaster confirmed the launches, and Iran closed its western airspace to brace for a possible response. Tehran had warned of retaliation after Israel struck Beirut’s southern suburbs without warning earlier Sunday in defiance of Washington’s request days ago to stand down. Israel said the Iranian-backed Hezbollah fired at northern Israel earlier in the day.

“Should these acts of aggression be repeated, the responses will be broader in scope and will encompass all American and Zionist targets throughout the region,” Iran’s Revolutionary Guard said in a statement that referenced attacks in Lebanon and on Iran’s coast and vessels around the Strait of Hormuz.

Sirens sounded in several areas of Israel, sending millions running for shelter. Israel’s military said it intercepted the missiles, and multiple explosions were heard in the north. Less than an hour later, the military said people could leave areas reinforced against missile attacks.

“Iran has made a grave mistake,” Israel military spokesperson Brig. Gen. Effie Defrin said. The military’s chief of staff, Lt. Gen. Eyal Zamir, said it will “strike the enemy with determination as soon as the order is given.”

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A streak of light illuminates the sky during an Iranian missile attack on Israel, as seen from Ashkelon on Sunday.Amir Cohen/Reuters

Iran had warned that an attack on Beirut would renew full-scale war across the Mideast, even as Pakistan and other mediators try to restart talks between Tehran and Washington.

“U.S. forces across the Middle East remain vigilant and ready,” the U.S. Central Command posted on X shortly before the missile launches.

The U.S. Embassy in Israel later directed employees and family members to shelter in place.

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Lebanese soldiers deploy at a road in front of destroyed houses in Dibbine village, southeast Lebanon, on Friday, a day after Israeli forces withdrew following clashes with Hezbollah fighters.Hussein Malla/The Associated Press

Israel’s attack on Beirut came a few days after the Lebanese and Israeli governments agreed to a ceasefire in U.S.-hosted talks, though Hezbollah rejected the deal. The strike on a residential building killed two people and wounded 20, Lebanon’s health ministry said.

“The army will continue to act in all of Lebanon,” the Israel military spokesperson said.

Israel’s strikes and ground invasion in Lebanon in pursuit of Hezbollah, and the militant group’s resistance to disarming, have complicated an overall deal to end the war in the Middle East.

Iran says any deal must include an end to fighting in Lebanon.

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Emergency personnel work at the site of an Israeli strike on the southern suburbs of Beirut, Lebanon, on Sunday.Mohamed Azakir/Reuters

Mr. Trump told a Fox News Channel reporter that he wanted the Iranians to stop firing missiles and return to the negotiating table. He also said that Israel’s strikes earlier Sunday were not co-ordinated with the U.S. and “I’m not happy about it.”

Israel on Monday had announced it would strike the southern suburbs of Lebanon’s capital, but urgent talks via Washington halted that on the condition that Hezbollah stop targeting Israeli border towns.

Hezbollah, which claimed responsibility for firing at Israel earlier Sunday, wants the direct talks between Lebanon and Israel to end. Instead, it supports Iran’s stance that an overall ceasefire deal between Tehran and Washington include the situation in Lebanon.

Mr. Netanyahu, who seeks re-election later this year, is under heavy domestic pressure to respond to both Iran and the Hezbollah threat, which has paralyzed life for thousands of residents along Israel’s northern border.

But Mr. Trump has made clear he does not want to see the war resume.

Mr. Trump said earlier Sunday in an interview with NBC’s Meet the Press that he would like to see a “more surgical attack on Hezbollah.” He also said he was “not demanding” that Lebanon be part of an overall ceasefire deal in the Iran war.

Iran continues to assert its grip on the Strait of Hormuz and the U.S. continues its blockade of Iranian ports, with shipments of oil, natural gas and fertilizer affected and the global economy in pain.

Iran since the ceasefire took effect has launched missiles and drones at Gulf nations and said it was targeting the U.S. military presence. After its launches against Israel, Iraq’s Civil Aviation Authority announced that the country’s airspace would close for 72 hours and Syria’s aviation authority announced a 12-hour airspace closure.

All flights from Tehran’s main international airport were suspended, the civil aviation authority said, according to the official Mizan news agency.

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Pakistan's Interior Minister Mohsin Naqvi in April, 2026. According to Iranian media, Mr. Naqvi met with Iran's Interior Minister Eskandar Momeni and Foreign Minister Abbas Araghchi this weekend.Pool/Reuters

Pakistan’s interior minister, Mohsin Naqvi, was in Tehran on Sunday delivering a message to Iranian Supreme Leader Ayatollah Mojtaba Khamenei from Pakistan’s army chief Field Marshal Asim Munir, according to Iran’s state-run IRNA news agency. There were no details on the message’s contents.

Mr. Khamenei has not been seen in public since he was named the Islamic Republic’s ruler after his father was killed on Feb. 28 as Israeli and U.S. strikes sparked the war.

Pakistani authorities have said Islamabad, with support from regional countries including Qatar, Turkey and Egypt, is working to help bridge differences.

In Cairo, the Egyptian and Qatari foreign ministers discussed “proposed elements” of a potential agreement between the U.S. and Iran, the Egyptian foreign ministry said, without details.

And after Iran’s missile launches at Israel, Iranian Foreign Minister Abbas Araghchi spoke with counterparts in France, Qatar, Saudi Arabia, Britain, Egypt and Turkey as well as Pakistan’s army chief of staff, Iran’s state TV said.

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